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reading MASH threads from 2024 and half of it aged badly
Long-ish post, sorry. tl;dr at the bottom. I have been tracking survodutide against triglycerides for 31 weeks because I could not find anyone who had. The correlation…
u/julia_mensa
Contributes reviews on supplier material. Based in Poznań.
member · joined 12 Mar 2025
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comment on [Paper] survodutide MASH data is the most interesting hepatic readout in the class in c/survodutide · 29 points · 2 days ago
MASH claims need the trial and the biopsy endpoint
comment on glucagon co-agonism has its own safety story, stop generalising from tirz in c/survodutide · 2 points · 3 days ago
hepatic fat and MASH are the story
comment on [Trial Data] phase 2 biopsy endpoints, and what "resolution" means in c/survodutide · 110 points · 6 days ago
four days. it took four days for me.
comment on stalled for 9 weeks at 12.5mg and I refuse to panic this time in c/survodutide · 5 points · 1 months ago
Hepatic fat or MASH or what?
comment on [Meta] the dual agonist rule is doing its job and people should stop complaining in c/survodutide · 6 points · 3 months ago
hepatic fat and survodutide are the story
comment on am I the only one who found biopsy harder than the injections in c/survodutide · 36 points · 3 months ago
Not convinced.
Disagree on that part. 97.4% and 97.6% on the same vial is normal.
comment on biopsy is the most under-discussed thing in c/bloodwork in c/survodutide · 6 points · 4 months ago
rodent dual agonist is investigation only
comment on [Question] Australia — has anyone got a straight answer on hepatic fat in c/survodutide · 112 points · 4 months ago
Yeah, glucagon co-agonism is genuinely different.
comment on anyone else notice survodutide kicking in around week 9 in c/survodutide · 1 points · 5 months ago
do not generalise from tirzepatide
comment on [Lab] SGN survo — VendorInvestigate came back 99.0% against a claimed 99.1% in c/survodutide · 42 points · 9 months ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on [Discussion] we are measuring MASH at the wrong time and calling it noise in c/survodutide · 36 points · 11 months ago
Every time this gets posted it hits the front page and every time someone has to re-explain it.
comment on three years of biopsy threads, summarised so you do not have to read them in c/survodutide · 67 points · 1 year ago
MASH claims need the trial and the biopsy endpoint
comment on three years of biopsy threads, summarised so you do not have to read them in c/survodutide · 29 points · 1 year ago
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
comment on reading MASH threads from 2024 and half of it aged badly in c/survodutide · 1 points · 2 years ago
the MASH indication changes the risk calculus
comment on reading MASH threads from 2024 and half of it aged badly in c/survodutide · 1 points · 2 years ago
The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.
comment on reading MASH threads from 2024 and half of it aged badly in c/survodutide · 0 points · 2 years ago
Came off after 89 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.
comment on 19 months in and hepatic fat is still the thing I get wrong in c/survodutide · 40 points · 2 years ago
Every time this gets posted it hits the front page and every time someone has to re-explain it.