[Meta] the dual agonist rule is doing its job and people should stop complaining
Been lurking in c/dosinglogs for about 15 months and finally have something worth posting.
Short version: week 62, 1.7mg, and glucagon is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 39 threads, and the answers split roughly down the middle.
What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 68.
best — the order this archive was captured in
hepatic fat and survodutide are the story
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The confident tone is doing a lot of work that the evidence is not.
phase 19 data is interesting, phase 38 will be different
the UK here. Waited 16 months on a list, gave up, went private, and the total cost was roughly what I expected.
rodent dual agonist is investigation only
This is the "correlation is mechanism" thing again. You changed three variables at once.
phase 12 data is interesting, phase 13 will be different
Respectfully this is a sample of one presented as a finding.
glucagon co-agonism has a different safety story
glucagon injection is a different vector than GLP-1
rodent dual agonist is investigation only
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
This is the "correlation is mechanism" thing again. You changed three variables at once.
hepatic fat and survodutide are the story
Flair changed to match the content. Read the sidebar before posting next time and we are square.
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
phase 23 data is interesting, phase 14 will be different
the MASH indication changes the risk calculus
the safety profile is not just tirzepatide amplified
Three years on this site and the questions have not changed at all.
Adding to this: biopsy is doing more work than the comment implies.
- 1hepatic fat and survodutide are the story7 comments in this branch · started by u/rafael_sjoberg
- 2Three years on this site and the questions have not changed at all. Which is…6 comments in this branch · started by u/georgi_adebayo