u/oskar_ibarra
Contributes reviews on supplier material. Based in Izmir.
member · joined 13 Apr 2025
comment on [Stats] relative risk reduction sells papers, absolute risk reduction makes decisions in c/trialwatch · 71 points · 2 days ago
comment on foam means you shook it. do not shake it in c/reconstitution · 72 points · 3 days ago
show your working or it is unhelpful
comment on [Question] does needle dead space actually matter at 2.5mg doses in c/reconstitution · 16 points · 4 days ago
Show the arithmetic. Where did the units come from?
comment on [Trial Data] STEP 1 vs SURMOUNT-1 side by side, with the caveats in c/trialwatch · 31 points · 5 days ago
SELECT reported a hazard ratio hazard ratio but the absolute event rate is what changes clinical practice.
comment on the food noise going quiet is the part nobody warned me about in c/semaglutide · 187 points · 8 days ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on [Math] someone check my arithmetic before i draw this up in c/reconstitution · 21 points · 9 days ago
Show the arithmetic. Where did the units come from?
comment on cloudy after reconstitution — discard, right? right. in c/reconstitution · 67 points · 13 days ago
Small correction: the trial was 3 weeks, not 4. Does not change your point but people will quote it.
comment on [Paper] ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests in c/trialwatch · 1 points · 16 days ago
give the trial name, phase, n, and primary endpoint in the body
comment on [Titration] stayed at 0.5 for eleven weeks and it was the right call in c/semaglutide · 54 points · 19 days ago
Half-life is about 168 hours, so steady state lands around week 7–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on does anyone else get one good week and one flat week on repeat in c/semaglutide · 4 points · 1 months ago
pens are overpriced, research vials are research grade, same molecule different price
comment on units — my 8-week log, condensed into one table in c/reconstitution · 7 points · 1 months ago
u-100 syringe, not u-40, or your math is off by factor of 4
comment on went back down from 2.4 to 1.7 and lost more. explain that in c/semaglutide · 0 points · 1 months ago
Half-life is about 168 hours, so steady state lands around week 4–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on STEP 1 was -14.9% average and i keep having to remind myself average means average in c/semaglutide · 23 points · 1 months ago
the injection-site soreness passes. i promise. not medical advice.
comment on [Lab] 19th independent test on TFC, and the trend is the interesting part in c/semaglutide · 32 points · 2 months ago
week 83 on the pen, 46kg down, this is the answer
comment on tried concentration for 23 weeks. here is what happened. in c/reconstitution · 128 points · 2 months ago
dosing errors come from people reconstituting two vials differently and forgetting which is which
comment on small win: units stopped being a problem at week 11 in c/reconstitution · 37 points · 3 months ago
more water means more units for the same dose, which means finer resolution
comment on [Discussion] the insulin syringe advice in here is 10 years out of date in c/reconstitution · 23 points · 3 months ago
dosing errors come from people reconstituting two vials differently and forgetting which is which
comment on [Discussion] bacteriostatic water is doing more work than we give it credit for in c/reconstitution · 1 points · 3 months ago
swirl, do not shake, or you are courting oxidation
comment on [Lab] SSA sema — Medutest came back 97.4% against a claimed 98.3% in c/semaglutide · 1 points · 3 months ago
okay but what dose of sema are you on
comment on [Discussion] bacteriostatic water is doing more work than we give it credit for in c/reconstitution · 18 points · 3 months ago
dead space is real and the syringe matters