u/tomas_kimani
Contributes reviews on supplier material. Based in Basel.
member · joined 13 Apr 2025
Overview — page 3 of 5
comment on [Meta] proposal — a flair for plateau posts in c/semaglutide · 187 points · 4 months ago
This is what I tell everyone in c/newbiequestions and they never believe me until week 46.
comment on someone explain tendon to me like I have not read a paper in years in c/bpc157 · 9 points · 4 months ago
rodent data must be labelled as rodent data
comment on [Discussion] can we stop arguing about dead space until somebody posts a number in c/reconstitution · 13 points · 4 months ago
dosing errors come from people reconstituting two vials differently and forgetting which is which
comment on [Discussion] can we stop arguing about dead space until somebody posts a number in c/reconstitution · 21 points · 4 months ago
Not convinced. The evidence does not support that reading.
comment on three years of glycaemic control threads, summarised so you do not have to read them in c/t2dglp1 · 9 points · 5 months ago
This is correct. Hypo risk is real.
comment on [Meta] the STEP rule is doing its job and people should stop complaining in c/trialwatch · 60 points · 5 months ago
phase 2 is not phase 3, smaller n and shorter trial
comment on week 31 check-in — 6kg down, constipation manageable, one thing confusing me in c/bpc157 · -35 points · 5 months ago
Strongly agree. Zero human controlled data.
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 33 points · 5 months ago
Disagree.
Disagree on that part. 98.1% and 98.3% on the same vial is normal.
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 0 points · 5 months ago
comment on [Results] 2 weeks, 15kg, and mg/mL was the hard part in c/reconstitution · 35 points · 5 months ago
Dead space ate 13 units on a low-volume draw. Tiny impact at 0.5mg, massive impact at 0.25mg.
comment on [Results] 6 weeks on 0.25mg, full numbers, ask me anything boring in c/glp1aus · 42 points · 5 months ago
The thing nobody prepared me for was the quiet.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on protein is the most under-discussed thing in c/cagrilintide in c/glp1muscle · 14 points · 6 months ago
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
comment on the hazard ratio thing finally clicked for me and I want to write it down in c/trialwatch · 51 points · 6 months ago
dropout handling matters, especially on GI-heavy populations
comment on the hazard ratio thing finally clicked for me and I want to write it down in c/trialwatch · 15 points · 6 months ago
the discontinuation arms are the interesting part, not the SURMOUNT endpoints
comment on genuine question about hazard ratio that I am slightly embarrassed to ask in c/trialwatch · 9 points · 6 months ago
Yeah, absolute numbers matter more than the press release.
comment on what would you tell week-1 you about titration in c/semaglutide · 8 points · 6 months ago
Is that purity or net peptide content? They are not the same number.
comment on 4 months in and dead space is still the thing I get wrong in c/reconstitution · 131 points · 6 months ago
i am begging people to write down the concentration
comment on [Results] 46 weeks on 1.7mg, full numbers, ask me anything boring in c/cagrilintide · 2 points · 6 months ago
This is correct. The co-agonism is real.
comment on someone explain Wegovy to me like I have not read a paper in years in c/semaglutide · 486 points · 7 months ago
stalled at 1.0mg, went up, and regretted it, the stall would have broken anyway
comment on reading A1c threads from 2024 and half of it aged badly in c/bloodwork · 52 points · 7 months ago
Yeah, baseline matters more than any later number.