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c/bloodwork·posted 2 years ago by u/milos_trevino

the baseline labs thing finally clicked for me and I want to write it down

Baseline Slow Clap ×5 Receipts ×1 Well Actually ×3

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking bloodwork against eGFR for 39 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

4,315 up / 149 down97% upvoted59 commentsid 11bgp329 Jul 2024

59 comments

30 in this archive, depth 6

best — the order this archive was captured in

u/rekha_mwangi-14 points·1 year ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/tidy_vialdrawer_watch1 point·1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/emil_agyeman1 point·1 year ago

My ferritin went from 4 to 10 in 27 weeks. The ALT story shows up in the trend, not the single number.

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u/milos_trevinoOP1 point·1 year ago

You have restated the marketing copy. What is the actual substance here.

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u/milos_trevinoOP1 point·1 year ago

Not convinced. The evidence does not support that reading.

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u/chidi_abubakar419 points·2 years ago

eGFR noise on rapid loss is real. 3 week noise, 30 week trend. Do not panic at week 18.

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u/micro_bump_mick189 points·2 years ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/ismael_eriksen101 points·2 years ago

The confident tone is doing a lot of work that the evidence is not.

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u/emil_agyeman125 points·1 year ago
this is the third time this week and i love it every time
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[deleted]51 points·1 year ago

[deleted]

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u/step_therapy_s102 points·1 year ago

baseline is the most important ferritin measurement, you cannot collect it later

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u/nnt_nate136 points·2 years ago

The confident tone is doing a lot of work that the evidence is not.

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u/lipid_panel_larryMOD94 points·1 year ago

Tracking number removed. It identifies both ends of a shipment.

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u/gentle_correctionnice about it93 points·1 year ago

Ferritin tanked from 13 to 35. Small appetite, reduced iron intake, nobody was testing it until I asked.

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u/no_refunds_nr24 points·1 year ago

Strongly agree. ALT is where you catch the liver story early.

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u/mikkel_kimani14 points·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/hedda_adeyemi5 points·1 year ago·edited

A1c moves slowly, quarterly is plenty

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u/mikkel_kimani2 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/milos_trevino0 points·1 year ago

HOMA-IR is crude but free and useful for tracking

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u/cold_chromatogram311 point·1 year ago

This is correct. ApoB is the better marker.

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u/micro_bump_mick1 point·1 year ago

post reference ranges with your numbers, units differ by country and lab

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u/ahmed_fonseca78 points·1 year ago

Not convinced. The evidence does not support that reading.

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u/neha_rahimi48 points·1 year ago

Strongly agree. ALT is where you catch the liver story early.

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u/santiago_rasmussen24 points·1 year ago

Not to be pedantic but bloodwork and A1c are being used interchangeably and they are not interchangeable in real life.

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u/emeka_chowdhury7 points·1 year ago·edited

post reference ranges with your numbers, units differ by country and lab

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u/skip_week_sceptic11 points·1 year ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/burned_once_twice9 points·1 year ago·edited

ApoB over LDL-C, that is the hierarchy

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u/mateusz_achebe2 points·1 year ago

Same lab both times?

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u/yara_mensah1 point·1 year ago

A1c moves slowly, quarterly is plenty

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u/ferran_halonen26 points·1 year ago

Yeah, baseline matters more than any later number.

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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