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Single comment threadYou are looking at one branch of stalled for 20 weeks at 10mg and I refuse to panic this time — 27 comments in the full submission. View in context.
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c/bloodwork·submitted 1 year ago by u/osman_eriksen

stalled for 20 weeks at 10mg and I refuse to panic this time

Discussionbranch of 8 comments

eGFR. That is the whole post, but I will justify it. Everything else people worry about in c/orforglipron is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort eGFR out first, and almost nobody does. I say this having got it wrong for 19 months. My fasting insulin…

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8 comments, started 1 year ago
u/kaia_kuusela31 points·1 year ago
controversial sort brought me here and it was worth it
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u/leila_vasquez25 points·1 year ago

Strongly agree. ALT is where you catch the liver story early.

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u/osman_eriksenOP-13 points·1 year ago

controversial sort brought me here and it was worth it

Adding to this: ApoB is doing more work than the comment implies.

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u/chidi_abubakar1 point·1 year ago

TSH from 9 to 22 is movement, not noise

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u/no_refunds_nr1 point·1 year ago

Strongly agree. ALT is where you catch the liver story early.

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u/cardio_endpoint_c15 points·1 year ago

eGFR noise during rapid loss is expected

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u/yara_boateng7 points·1 year ago

HOMA-IR is crude but free and useful for tracking

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[removed]5 points·1 year ago

[removed by moderator]

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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