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c/bloodwork·submitted 2 months ago by u/constipation_club

reading bloodwork threads from 2024 and half of it aged badly

Resultsbranch of 7 comments

eGFR. That is the whole post, but I will justify it. Everything else people worry about in c/orforglipron is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort eGFR out first, and almost nobody does. I say this having got it wrong for 13 months. My fasting insulin…

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7 comments, started 2 months ago
u/liver_enzyme_liz111 points·2 months ago

Half-life is about 168 hours, so steady state lands around week 22–5. Practical consequence: what you feel in week 1 is not what that dose does.

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u/greta_chukwu-15 points·2 months ago

Slight fix: the number was 98.7, not 98.3. Decimal point, but a fairly consequential one.

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u/ismael_eriksen1 point·2 months ago

nobody here can tell you what a result means for you

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u/amara_dziedzic1 point·2 months ago

Yeah, baseline matters more than any later number.

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u/lina_falk1 point·2 months ago

nobody here can tell you what a result means for you

Yes, exactly this, and it is the bit that took me 42 weeks to accept.

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u/skip_week_sceptic1 point·2 months ago·edited

A1c moves slowly, quarterly is plenty

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u/intent_to_treat1 point·2 months ago

eGFR noise during rapid loss is expected

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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