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c/bloodwork·posted 8 months ago by u/emeka_chowdhury

[Question] ALT — what am I missing here

Question Long Haul ×3

Quick one. Canada here.

ferritin works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 7 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

835 up / 182 down82% upvoted28 commentsid xspmn24 Nov 2025

28 comments

23 in this archive, depth 4

best — the order this archive was captured in

u/anders_vermeulen118 points·8 months ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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[deleted]88 points·8 months ago

[deleted]

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u/peptidemeter_pat56 points·8 months ago

triglycerides from 23 to 16 is movement, not noise

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u/emeka_chowdhuryOP43 points·8 months ago

My A1c went from 4 to 6 in 73 weeks. The ALT story shows up in the trend, not the single number.

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u/andres_restrepo43 points·8 months ago

ferritin tanks quietly on a reduced appetite, check it

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u/jarno_karlsen31 points·8 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/yara_boateng-10 points·8 months ago

ApoB over LDL-C, that is the hierarchy

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u/cardio_endpoint_c1 point·8 months ago

ApoB over LDL-C, that is the hierarchy

Adding to this: ALT is doing more work than the comment implies.

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u/hedda_adeyemi87 points·8 months ago

This is correct. ApoB is the better marker.

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u/gentle_correctionMOD41 points·8 months ago

Retitled to remove editorialising. Put the evidence in the body.

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u/hugo_pires49 points·8 months ago

HOMA-IR is crude but free and useful for tracking

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u/osman_eriksen25 points·8 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/kaia_kuusela20 points·8 months ago·edited

HOMA-IR is crude but free and useful for tracking

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u/emeka_chowdhuryOP10 points·8 months ago

eGFR noise during rapid loss is expected

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u/ferran_halonen34 points·8 months ago

A1c moves slowly, quarterly is plenty

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u/edit_for_clarity23 points·8 months ago

ApoB from 23 to 27 is movement, not noise

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u/nabila_bakken11 points·8 months ago·edited

TSH from 24 to 19 is movement, not noise

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u/transit_variance39 points·8 months ago

Ferritin tanked from 6 to 13. Small appetite, reduced iron intake, nobody was testing it until I asked.

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u/mateusz_achebe33 points·8 months ago

ApoB over LDL-C, that is the hierarchy

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u/jonas_cardoso38 points·8 months ago

ApoB over LDL-C, that is the hierarchy

Adding to this: ALT is doing more work than the comment implies.

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u/emeka_chowdhuryOP16 points·8 months ago

ALT is where the fatty-liver story shows up first

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u/greta_chukwu19 points·8 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/cold_chromatogram3115 points·8 months ago·edited

What are your reference ranges?

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About c/bloodwork

What to measure before you start, what to re-measure, and how to interpret movement without panicking. ApoB over LDL-C, HOMA-IR as a crude free tool, ALT and the fatty-liver story, eGFR noise during rapid loss, and the deficiencies that a 1,100-calorie appetite will hand you.

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