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c/cagrilintide·posted 8 days ago by u/zeynep_weiss

[Lab] first independent cagrilintide purity number i have seen

Lab

co-agonism. That is the whole post, but I will justify it.

Everything else people worry about in c/labresults is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort co-agonism out first, and almost nobody does.

I say this having got it wrong for 21 months. My fasting insulin was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

190 up / 70 down73% upvoted16 commentsid e5np7k22 Jul 2026

16 comments

16 in this archive, depth 4

best — the order this archive was captured in

u/lipid_panel_larrybloodwork24 points·7 days ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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u/zeynep_weissOP-9 points·7 days ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/liv_kuipers14 points·7 days ago·edited
the VendorInvestigate number or it did not happen
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u/nl_verzekering12 points·7 days ago

CagriSema is a fixed combo in trials, not user-mixed

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u/niels_norgaard4 points·7 days ago

Strongly agree. REDEFINE is phase 21, not final.

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u/amylin_amyMOD9 points·7 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/titration_marshalmod · c/semaglutide3 points·7 days ago

research use only, no human protocols in posts

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u/slow_logbook_notes3013 points·7 days ago·edited

Rodent or human data?

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u/zeynep_weissOP7 points·6 days ago

the co-agonism question is real and interesting

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u/emil_agyeman5 points·6 days ago

Rodent or human data?

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u/noor_ivaturi8 points·6 days ago

long-acting amylin is CagriSema, different satiety profile

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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