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Single comment threadYou are looking at one branch of [Trial Data] REDEFINE 1 — what cagri adds on top of sema — 27 comments in the full submission. View in context.
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c/cagrilintide·submitted 4 days ago by u/noor_ivaturi

[Trial Data] REDEFINE 1 — what cagri adds on top of sema

Trial Databranch of 10 comments

Genuinely asking, not being difficult. Everyone in c/reconstitution repeats that satiety is important. I believe it, but I have never seen anyone show why, and when I search I get 21 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

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10 comments, started 3 days ago
u/egfr_watcher41 points·3 days ago

You have restated the marketing copy. What is the actual substance here.

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u/noor_ivaturiOP26 points·2 days ago

REDEFINE phase 9 readouts are interesting but 9 person cagrilintide is different from 9 trial cagrilintide.

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u/b12_baseline21 points·2 days ago

amylin receptor distribution is different from GLP-1

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u/zeynep_zielinski13 points·2 days ago

This is correct. The co-agonism is real.

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u/ledger_modMOD22 points·2 days ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/noor_ivaturiOP13 points·2 days ago

not approved anywhere, keep posts descriptive, not instructional

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[removed]19 points·2 days ago

[removed by moderator]

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u/noor_ivaturiOP0 points·2 days ago

I am going to push back on this slightly.

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u/nadia_fonseca9 points·2 days ago·edited

not approved anywhere, keep posts descriptive, not instructional

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u/slow_logbook_notes3016 points·2 days ago

Rodent or human data?

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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