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c/coa·submitted 1 year ago by u/wrong_network_w

stalled for 23 weeks at 5mg and I refuse to panic this time

Explainerbranch of 9 comments

purity. That is the whole post, but I will justify it. Everything else people worry about in c/sideeffects is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort purity out first, and almost nobody does. I say this having got it wrong for 20 months. My eGFR…

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9 comments, started 1 year ago
u/andres_restrepo769 points·1 year ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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[deleted]551 points·1 year ago

[deleted]

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u/wrong_network_wOP207 points·1 year ago

no "is this good?" without saying what the compound and claimed purity are

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u/wrong_network_wOP149 points·1 year ago

Four months on the site and I was confusing area% and mass% in every post I made. One explainer thread and it clicked.

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u/anecdata_annie180 points·1 year ago

Strongly agree. Mass% and area% are answering different questions on the same document.

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u/marisol_frisk40 points·1 year ago

Not to be pedantic but water content and batch are being used interchangeably and they are not interchangeable in real life.

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u/yannick_haddad16 points·1 year ago

the method line is doing real work, not just window dressing

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How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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