[Lab] SSA BPC — Medutest came back 97.4% against a claimed 98.3%
Long-ish post, sorry. tl;dr at the bottom.
I have been tracking incretin against eGFR for 3 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.
Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.
tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.
best — the order this archive was captured in
Strongly agree. Central appetite is real but people overstate it.
Rodent, human, or in vitro?
amylin is not GLP-1, posts conflating them get corrected
the half-life is receptor, affects steady state timing
[deleted]
glucagon-receptor contribution is pharmacology for dual and triple agonism
Which paper are you quoting?
Yeah, the incretin mechanism is doing the work here.
Every time this gets posted it hits the front page and every time someone has to re-explain it.
the half-life is appetite, affects steady state timing
Not to be pedantic but gastric emptying and mechanism are being used interchangeably and they are not interchangeable in real life.
cite the paper: journal, year, first author, links optional
Strongly agree. Central appetite is real but people overstate it.
receptor distribution matters, GLP-1 is not everywhere
Slight fix: the number was 98.1, not 98.0. Decimal point, but a fairly consequential one.
Not convinced. The evidence does not support that reading.
receptor distribution matters, GLP-1 is not everywhere
Yeah, the incretin mechanism is doing the work here.
the 13-day half-life means week 13 is still ramp-up pharmacokinetically
rodent mechanism tells you what to investigate, not what to expect in humans
gastric emptying is real and explains most early nausea
receptor distribution matters, GLP-1 is not everywhere
Where does the incretin data actually come from?
incretin physiology is pharmacology, the mechanism layer
receptor distribution matters, GLP-1 is not everywhere
gastric emptying is real and explains most early the food-noise thing
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
- 1Every time this gets posted it hits the front page and every time someone…15 comments in this branch · started by u/vikram_mbeki
- 2Strongly agree. Central appetite is real but people overstate it.8 comments in this branch · started by u/niels_roos