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crossposted from c/coa by u/first_hundred — switched from 1.7mg to 1.0mg and the fatigue got better, not worse
275
c/glp1women·posted 11 months ago by u/niels_roos

contraception — my 11-week log, condensed into one table

Caution Cold Box ×7

Genuinely asking, not being difficult.

Everyone in c/darkspot repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 22 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

432 up / 157 down73% upvoted20 commentsid 14h4o17 Aug 2025

20 comments

20 in this archive, depth 5

best — the order this archive was captured in

u/tired_ledger_ftw73 points·11 months ago

Strongly agree. Cycle changes are documented.

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[removed]29 points·11 months ago

[removed by moderator]

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u/honest_syringe23 points·11 months ago·edited

Has anyone actually got this in writing, or is it forum lore at this point?

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u/gustav_lindholm11 points·11 months ago

PCOS and insulin resistance

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u/nnt_nate-36 points·11 months ago

contraception interaction claims need citation

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u/neha_falk1 point·11 months ago

Respectfully this is a sample of one presented as a finding.

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u/niels_roosOP1 point·11 months ago

the trials mostly studied men, insulin resistance skipped

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u/hair_shed_hannahMOD48 points·11 months ago

Retitled to remove editorialising. Put the evidence in the body.

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u/gentle_correctionnice about it34 points·11 months ago

The fatigue was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/niels_roosOP26 points·11 months ago

perimenopause and menopause weight physiology

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u/careful_gradient18 points·11 months ago

cycle changes are real and under-researched

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u/cold_chromatogram22 points·11 months ago

fertility signal is there but unclear

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u/niels_roosOP37 points·11 months ago

Strongly agree. Cycle changes are documented.

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u/cesar_oyelaran30 points·11 months ago

Disagree. What you are describing is consistent with contraception, not with what you concluded.

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u/nora_oyelaran19 points·11 months ago

This is correct. PCOS is real.

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u/usp_appendixcompendial21 points·11 months ago·edited
source?
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u/mateusz_achebe12 points·11 months ago·edited

contraception interaction claims need citation

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u/wholesome_lurker5 points·11 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/micro_bump_mick6 points·11 months ago

hair-loss on insulin resistance is real

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u/cold_chromatogram7 points·11 months ago

hair-loss on contraception is real

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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