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c/orforglipron·submitted 2 months ago by u/kavya_radich

[PSA] non-peptide is not what most of this community thinks it is

Questionbranch of 9 comments

Confession thread, sort of. I went from 2.5mg to 1.0mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 16 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have muscle…

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9 comments, started 2 months ago
u/bruno_dumitru5 points·2 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/rasmus_petrescu2 points·2 months ago

the small molecule is whether this actually works long-term

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u/dario_boateng0 points·2 months ago

oral non-peptide agonist is small molecule, no food restrictions

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u/lukas_delgado1 point·2 months ago

the supply conversation changes if this approves

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u/piotr_bruun-13 points·2 months ago

Slight fix: the number was 99.1, not 96.8. Decimal point, but a fairly consequential one.

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u/kavya_radichOP1 point·2 months ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/blank_injection1 point·2 months ago

Which country? Half the answers in this thread only apply in Spain.

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u/erez_yilmaz1 point·2 months ago

the absorption problem is solved by non-peptide structure

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u/trialwatch_theotrial nerd1 point·2 months ago

the small molecule is whether this actually works long-term

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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