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Single comment threadYou are looking at one branch of orforglipron vs ATTAIN — genuinely asking which matters more — 58 comments in the full submission. View in context.
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c/orforglipron·submitted 1 year ago by u/maren_sorensen

orforglipron vs ATTAIN — genuinely asking which matters more

Trial Databranch of 4 comments

ACHIEVE. That is the whole post, but I will justify it. Everything else people worry about in c/survodutide is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort ACHIEVE out first, and almost nobody does. I say this having got it wrong for 9 months. My eGFR…

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4 comments, started 1 year ago
u/salma_almeida132 points·1 year ago·edited

Not convinced. The evidence does not support that reading.

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u/tobias_molnar32 points·1 year ago·edited

availability speculation must be flaired Speculation

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u/marit_coelho-27 points·1 year ago

oral non-peptide agonist is ACHIEVE, no food restrictions

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[deleted]1 point·1 year ago

[deleted]

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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