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Single comment threadYou are looking at one branch of unpopular opinion: orforglipron is massively overrated — 47 comments in the full submission. View in context.
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c/orforglipron·submitted 1 year ago by u/sofia_petrescu

unpopular opinion: orforglipron is massively overrated

Speculationbranch of 8 comments

Posting this because I searched for it and got nothing useful. Setup: 12.5mg, week 82, sulphur burps present but not ruining anything. I changed exactly one variable — non-peptide — and tracked it for 23 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it.…

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8 comments, started 1 year ago
u/ravi_sandvik73 points·1 year ago

Strongly agree. The supply impact would be huge.

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u/kenji_kimani51 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/mateusz_mensah32 points·1 year ago

small molecule purity is different testing than peptides

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u/santiago_villalobos19 points·1 year ago

Yeah, small molecule changes the whole game.

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u/marit_sandvik28 points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/sofia_petrescuOP46 points·1 year ago

Not convinced. The evidence does not support that reading.

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u/anders_karlsen53 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/declared_value_dv36 points·1 year ago

small molecule purity is different testing than peptides

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