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stalled for 18 weeks at 7.5mg and I refuse to panic this time
Long-ish post, sorry. tl;dr at the bottom. I have been tracking orforglipron against eGFR for 11 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one…
Week 49 for me and the honest summary is: 28kg down, early fullness manageable, and I have thought about food maybe four times today.
Yeah, small molecule changes the whole game.
The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.
This is the "correlation is mechanism" thing again. You changed three variables at once.