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c/orforglipron·submitted 8 months ago by u/freya_marchand

what would you tell week-1 you about ATTAIN

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Week 2 update. 13kg down from the start, muscle cramps basically gone since about week 54. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps. The part that surprised me is how much of this is admin.…

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4 comments, started 8 months ago
u/salma_almeida101 points·8 months ago

the fatigue profile is speculative at this stage

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u/ayesha_erdogan-34 points·8 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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