GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of is it normal to get constipation at week 14 — 44 comments in the full submission. View in context.
968
c/orforglipron·submitted 7 months ago by u/maren_sorensen

is it normal to get constipation at week 14

Questionbranch of 10 comments

Right, the oral GLP-1 question again, but with numbers this time. I have 20 data points over 4 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

Read the full submission and all 44 comments →

This branch

10 comments, started 7 months ago
u/hsa_math13 points·7 months ago

Strongly agree. The supply impact would be huge.

replysharereportpermalink
u/whois_wanda15 points·7 months ago

Not convinced. The evidence does not support that reading.

replysharereportpermalink
u/canada_coverage6 points·7 months ago

What are you comparing it against though?

replysharereportpermalink
u/purity_pedantanalytical3 points·7 months ago

oral non-peptide agonist is orforglipron, no food restrictions

replysharereportpermalink
u/zeynep_ndiaye0 points·7 months ago

Strongly agree. The supply impact would be huge.

replysharereportpermalink
u/joaquin_trevino1 point·7 months ago

the nausea profile is speculative at this stage

replysharereportpermalink
load more comments (3) →
u/ice_pack_auditcold chain5 points·7 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

replysharereportpermalink

← back to the whole thread

About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

21kmembers
62submissions
Feb 2024created
submissions / month, last year
Sponsored

Sigma-Aldrich Standards

Certified reference materials for peptide identity and purity work.

sigmaaldrich.com
More in c/orforglipron
c/orforglipron rules
  1. Small molecule, not a peptide. Purity discussion here is a different problem.
  2. Cite ATTAIN/ACHIEVE arms specifically when quoting numbers.
  3. Availability speculation must be flaired Speculation.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/incretin_ivyu/phase_two_peteu/trialwatch_theo
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →