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c/reconstitution·posted 7 months ago by u/viktor_erdogan

[Question] how do you actually verify dead space

Question Receipts ×7 Well Actually ×2

Week 9 update. 40kg down from the start, muscle cramps basically gone since about week 49.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

2,109 up / 533 down80% upvoted60 commentsid 91hgxn13 Dec 2025

60 comments

30 in this archive, depth 6

best — the order this archive was captured in

u/cesar_ivaturi147 points·7 months ago

Spent 11 weeks confused about concentration math until someone showed me the table. 20mg, 2mL, concentration is 20/2.

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u/viktor_erdoganOP105 points·7 months ago

bacteriostatic and sterile water are not interchangeable, do not use them that way

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u/cesar_ivaturi51 points·7 months ago

dead space is real and the syringe matters

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u/elodie_grimaldi40 points·7 months ago·edited

Cosigning. The concentration on the vial in marker is load-bearing.

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u/a1c_arcT2D31 points·7 months ago

dead space is real and the syringe matters

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[removed]69 points·7 months ago

[removed by moderator]

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u/ismael_nwosu37 points·7 months ago

i am begging people to write down the concentration

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u/bac_water_banditMOD121 points·7 months ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/lyophile_lou-5 points·7 months ago

Spent 17 weeks confused about concentration math until someone showed me the table. 10mg, 2mL, concentration is 10/2.

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u/tuva_kirchner95 points·7 months ago·edited

Is that 10mg vial or 11mg?

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u/rosa_mensah49 points·7 months ago

u-100 syringe, not u-40, or your math is off by factor of 15

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u/viktor_erdoganOP93 points·7 months ago

The single most useful thing I did was write the concentration on the vial. Stopped all the confusion after that.

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u/rasmus_kuipers59 points·7 months ago

Show the arithmetic. Where did the units come from?

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u/bac_water_banditreconstitution20 points·7 months ago

bacteriostatic and sterile water are not interchangeable, do not use them that way

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u/santiago_ndiaye70 points·7 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/georgi_adebayo44 points·7 months ago

Cosigning. The concentration on the vial in marker is load-bearing.

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u/erez_perrin16 points·7 months ago

dead space is real and the syringe matters

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u/hub_opssite staff75 points·7 months ago

The single most useful thing I did was write the concentration on the vial.

Disagree on that part. 98.9% and 99.0% on the same vial is normal.

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u/erez_perrin50 points·7 months ago

stopper coring on the 24th draw because you keep using the same entry point. rotate.

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u/hedda_adeyemi14 points·7 months ago·edited

stopper coring on the 24th draw because you keep using the same entry point.

Disagree on that part. 99.2% and 97.6% on the same vial is normal.

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u/viktor_erdoganOP47 points·7 months ago

20mg vial, 2mL water, concentration is 20/2 — write it on the vial afterwards

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u/georgi_adebayo12 points·7 months ago

dead space is real and the syringe matters

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u/rosa_mensah5 points·7 months ago

Are you using a u-100 or u-40 syringe? That changes everything.

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u/andres_sorensen16 points·7 months ago

the concentration on the vial in marker is the most important step

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u/sleep_apnea_sam13 points·7 months ago·edited

Yeah, showing the arithmetic is the fastest way for someone to spot the error.

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u/georgi_adebayo81 points·7 months ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

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u/priya_guerrero44 points·7 months ago

dosing errors come from people reconstituting two vials differently and forgetting which is which

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/andres_sorensen59 points·7 months ago

This is correct. 2mL versus 9mL is the common mistake.

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u/arne_restrepo30 points·7 months ago·edited

You have restated the marketing copy. What is the actual substance here.

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u/hedda_adeyemi8 points·7 months ago

i am begging people to write down the concentration

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About c/reconstitution

The arithmetic and the technique. Bacteriostatic versus sterile water, reconstitution volume as a concentration choice, converting mg/mL into insulin-syringe units, dead space, swirl-not-shake, stopper coring, and how long a reconstituted vial is actually good for. Math errors get corrected fast and politely.

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