[Question] why is reta purity testing so much more variable between labs
Been lurking in c/progresspics for about 7 months and finally have something worth posting.
Short version: week 28, 15mg, and TRIUMPH is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 31 threads, and the answers split roughly down the middle.
What I actually want to know is whether the people saying it does not matter have measured it, or whether it is just repeated confidently. Happy to be told I am overthinking this — I probably am — but I would rather overthink it now than at week 22.
best — the order this archive was captured in
The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.
This is correct. Triple agonism is genuinely different.
This is correct. Triple agonism is genuinely different.
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
the weight curves are unusually steep, which makes predicting individual response harder
retatrutide is not approved anywhere for human use, posts must not read as instructions
What was the dosing schedule in that arm?
the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
Yes, exactly this, and it is the bit that took me 20 weeks to accept.
I am going to push back on this slightly.
the glucagon component changes the side effect profile, not just the efficacy
This is correct. Triple agonism is genuinely different.
heart rate and dose escalation need actual measurements, not impressions
Disagree but this is the good kind of wrong — it is specific enough to be checked.
TRIUMPH phase 2 showed 99.3% weight loss but the injection-site soreness profile on the highest arm was rough. Phase 2 != phase 3.
- 1This is correct. Triple agonism is genuinely different.9 comments in this branch · started by u/lane_watcher
- 2I am going to push back on this slightly.7 comments in this branch · started by u/iman_castellanos