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c/retatrutide·posted 15 days ago by u/blunt_coldbox_2024

[Caution] "just start at 2mg" is the worst advice in this community

Caution

Something I noticed reading old threads that I have not seen said out loud.

The advice on TRIUMPH in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with the same confidence.

I have listed what I think the current consensus is below. Correct me — that is the point of posting it.

327 up / 88 down79% upvoted13 commentsid 1yh0wy14 Jul 2026

13 comments

12 in this archive, depth 4

best — the order this archive was captured in

u/honest_syringe_202519 points·15 days ago
oh thank god it is not just me
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u/blunt_coldbox_2024OP8 points·15 days ago

The glucagon component does different things than dual agonism. The reflux are not just amplified versions.

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u/mateusz_mensah3 points·14 days ago

the 0.5mg arm is different from 12.5mg, results do not transfer

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u/cagrilintide_enthusiast1 point·14 days ago·edited

The confident tone is doing a lot of work that the evidence is not.

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u/iman_castellanos14 points·14 days ago·edited
this is the answer
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u/tired_ledger_notes12 points·14 days ago

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/source_or_silence15 points·14 days ago

Not to be pedantic but retatrutide and triple agonist are being used interchangeably and they are not interchangeable in real life.

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u/helga_vermeulen8 points·14 days ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/blunt_coldbox_2024OP-2 points·13 days ago

Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.

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u/halima_mbeki4 points·14 days ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

Yes, exactly this, and it is the bit that took me 73 weeks to accept.

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u/two_mil_or_one0 points·14 days ago

the weight curves are unusually steep, which makes predicting individual response harder

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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