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c/retatrutide·submitted 1 year ago by u/lurker_for_years

someone explain glucagon to me like I have not read a paper in years

Trial Databranch of 5 comments

I have had 23 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 38 days on nominally the same lane, which matters more in summer than in February. The independent number came back 97.9% against a claimed…

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5 comments, started 1 year ago
u/marta_vanhecke65 points·1 year ago

This is correct. Triple agonism is genuinely different.

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u/matias_falk49 points·1 year ago

the 1.7mg arm is different from 1.0mg, results do not transfer

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u/devils_advocate_d39 points·1 year ago

the dosing is steep, the early fullness reports are real, and nobody knows the human safety yet

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u/tired_ledger_notes14 points·1 year ago

Small correction: the trial was 16 weeks, not 39. Does not change your point but people will quote it.

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u/yannick_salinas16 points·1 year ago·edited

Slight fix: the number was 99.1, not 99.0. Decimal point, but a fairly consequential one.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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