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c/retatrutide·submitted 2 years ago by u/nikhil_asante

anyone else notice phase 2 kicking in around week 19

Resultsbranch of 11 comments

Right, the triple agonist question again, but with numbers this time. I have 4 data points over 20 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign. The thing I would flag for anyone new: the effect I am…

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11 comments, started 2 years ago
u/vito_beaulieu263 points·2 years ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/lina_bruun81 points·2 years ago·edited

Strongly agree. Heart rate escalation needs the actual data, not impressions.

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u/ledger_modMOD163 points·2 years ago

Tracking number removed. It identifies both ends of a shipment.

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u/nikhil_asanteOP0 points·2 years ago

retatrutide is not approved anywhere for human use, posts must not read as instructions

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u/jarno_cabrera1 point·2 years ago

the glucagon component changes the side effect profile, not just the efficacy

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u/nikhil_asanteOP1 point·2 years ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/ewan_marchand1 point·2 years ago

phase 2 numbers are not maintenance numbers, cite the trial

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u/heart_rate_bump1 point·2 years ago

Not to be pedantic but dose escalation and retatrutide are being used interchangeably and they are not interchangeable in real life.

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u/trialwatch_theotrial nerd1 point·2 years ago

the glucagon component changes the side effect profile, not just the efficacy

Adding to this: TRIUMPH is doing more work than the comment implies.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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  1. Retatrutide is not approved anywhere for human use. Posts must not read as usage instructions.
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  3. Heart-rate and dose-escalation reports need actual measurements, not impressions.
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