anyone else notice phase 2 kicking in around week 19
Right, the triple agonist question again, but with numbers this time.
I have 4 data points over 20 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.
The thing I would flag for anyone new: the effect I am describing showed up at week 49, not week 3. People give up long before the interesting part.
Interested in whether this matches other people's logs or whether I am an outlier.
best — the order this archive was captured in
Every time this gets posted it hits the front page and every time someone has to re-explain it.
Strongly agree. Heart rate escalation needs the actual data, not impressions.
Tracking number removed. It identifies both ends of a shipment.
retatrutide is not approved anywhere for human use, posts must not read as instructions
the glucagon component changes the side effect profile, not just the efficacy
Sceptical. If this were true we would see it reflected in the data and we do not.
phase 2 numbers are not maintenance numbers, cite the trial
Not to be pedantic but dose escalation and retatrutide are being used interchangeably and they are not interchangeable in real life.
the glucagon component changes the side effect profile, not just the efficacy
Adding to this: TRIUMPH is doing more work than the comment implies.
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
That is net peptide content, not purity. Different number, different meaning.
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
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Did you actually measure heart rate or is that a feeling?
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
Did you actually measure heart rate or is that a feeling?
the weight curves are unusually steep, which makes predicting individual response harder
The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
TRIUMPH phase 2 showed 98.0% weight loss but the constipation profile on the highest arm was rough. Phase 2 != phase 3.
The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.
The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.
retatrutide is not approved anywhere for human use, posts must not read as instructions
the 10mg arm is different from 12.5mg, results do not transfer
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
I am going to push back on this slightly.
- 1Every time this gets posted it hits the front page and every time someone…11 comments in this branch · started by u/vito_beaulieu
- 2The practical rule people converge on is 28 days at fridge temperature after…6 comments in this branch · started by u/cold_chromatogram_only