[Discussion] TRIUMPH is doing more work than we give it credit for
Trying to settle this properly because the thread from last year went in circles.
The claim: glucagon matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 14 months without either producing anything.
What would actually settle it is 17 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.
If you have data, post the data. If you have an opinion, flair it as an opinion.
best — the order this archive was captured in
heart rate and dose escalation need actual measurements, not impressions
heart rate and dose escalation need actual measurements, not impressions
Yes, exactly this, and it is the bit that took me 52 weeks to accept.
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Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
the dosing is steep, the fatigue reports are real, and nobody knows the human safety yet
heart rate and dose escalation need actual measurements, not impressions
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
phase 2 numbers are not maintenance numbers, cite the trial
This is correct. Triple agonism is genuinely different.
- 1heart rate and dose escalation need actual measurements, not impressions8 comments in this branch · started by u/nikhil_lindqvist