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c/retatrutide·posted 8 months ago by u/yannick_barros

am I the only one who found TRIUMPH harder than the injections

Caution Cold Box ×3 Slow Clap ×2 Clean Column ×2

phase 2. That is the whole post, but I will justify it.

Everything else people worry about in c/glp1canada is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort phase 2 out first, and almost nobody does.

I say this having got it wrong for 18 months. My eGFR was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

3,088 up / 295 down91% upvoted12 commentsid y4vsp029 Nov 2025

12 comments

7 in this archive, depth 4

best — the order this archive was captured in

u/noor_ivaturi308 points·8 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/cold_chromatogram_only219 points·8 months ago
this deserves more than 21 upvotes
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u/yannick_barrosOP157 points·8 months ago

Small correction: the trial was 3 weeks, not 14. Does not change your point but people will quote it.

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u/farid_molnar47 points·8 months ago

nobody should be giving this to anyone without extensive monitoring

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[deleted]21 points·8 months ago

[deleted]

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u/ewan_marchand176 points·8 months ago

TRIUMPH phase 2 showed 97.4% weight loss but the fatigue profile on the highest arm was rough. Phase 2 != phase 3.

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u/reta_and_regretMOD123 points·8 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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About c/retatrutide

Retatrutide: GIP/GLP-1/glucagon triple agonism, the TRIUMPH programme, and the fact that most people discussing it are handling research-grade material with no human-use approval anywhere. Dose-response, heart-rate signal, and the unusually steep phase-2 weight curves get argued about here weekly.

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