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c/sideeffects·posted 2 months ago by u/marta_marchand

what would you tell week-1 you about fatigue

Discussion Clean Column ×8 Sourced ×1

Week 31 update. 7kg down from the start, reflux basically gone since about week 71.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

1,327 up / 331 down80% upvoted36 commentsid 1b15vu25 May 2026

36 comments

26 in this archive, depth 5

best — the order this archive was captured in

u/chidi_demir61 points·2 months ago

Disagree. What you are describing is consistent with gallbladder, not with what you concluded.

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u/nausea_notesMOD32 points·2 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/rania_marchand26 points·2 months ago

Are you on a pen or research vial? The formulation changes the profile.

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u/rina_bergstrom-38 points·2 months ago

early fullness at 15mg is different from 1.7mg

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u/marta_marchandOP0 points·2 months ago

week 27 and the injection-site soreness is finally getting better

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u/idris_iyer9 points·2 months ago

nausea on day 2 is normal, nausea after week 33 is worth checking

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u/slow_logbook_ftw7 points·2 months ago·edited

severe abdominal pain is an urgent-care question, not a forum question

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u/ferran_dahlberg37 points·2 months ago
saved. thank you.
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u/amara_haddad8 points·2 months ago

saved.

Yes, exactly this, and it is the bit that took me 81 weeks to accept.

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u/bastian_eriksen4 points·2 months ago

the muscle cramps passes. i promise. not medical advice.

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u/tl_dr_tina12 points·2 months ago

Same experience. Week 84 and it simply stopped. I know that is not useful information but it is what happened.

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u/quiet_moderatormod3 points·2 months ago

This is correct. The injection-site soreness is horrible for three weeks and then just ends.

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u/peptidemeter_pat33 points·2 months ago

My fatigue was worst at 1.7mg and better at 1.0mg, which makes no sense but it is real.

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u/liv_okafor21 points·2 months ago

Same experience. Week 64 and it simply stopped. I know that is not useful information but it is what happened.

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u/usp_appendixcompendial24 points·2 months ago

constipation is real, boring, and fixable

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u/marta_marchandOP12 points·2 months ago

How many weeks in are you? 14 weeks is noise, 29 weeks is a trend.

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u/food_noise_gonemaintenance18 points·2 months ago

Disagree. What you are describing is consistent with fatigue, not with what you concluded.

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u/rina_bergstrom13 points·2 months ago

Disagree.

Disagree on that part. 95.1% and 99.3% on the same vial is normal.

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u/enzo_danquah12 points·2 months ago

sulphur burps are disgusting but not dangerous, 21 weeks and they stopped

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u/hassan_castellanos8 points·2 months ago

This is correct. The sulphur burps is horrible for three weeks and then just ends.

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u/tomas_broberg10 points·2 months ago

Did the nausea start before or after the dose increase?

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u/halima_mbeki6 points·2 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/isabela_nilsen4 points·2 months ago

Same experience. Week 54 and it simply stopped. I know that is not useful information but it is what happened.

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u/saskia_lokken3 points·2 months ago

Strongly agree. Describe your dose, your week number, and your titration speed or nobody can help.

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u/marta_marchandOP2 points·2 months ago

Went to A&E convinced it was pancreatitis. Lipase normal. It was gallstones. Get checked, do not post and wait.

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u/adaeze_brandt1 point·2 months ago

Went to A&E convinced it was pancreatitis.

Yes, exactly this, and it is the bit that took me 66 weeks to accept.

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About c/sideeffects

Side-effect experience and management, with a strong bias toward the ones that are common and boring (nausea, constipation, reflux, fatigue, sulphur burps) and a hard line on the ones that are not (severe abdominal pain, persistent vomiting, jaundice, vision changes). This community is not a substitute for urgent care and the mods will say so bluntly.

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