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c/sideeffects·posted 8 months ago by u/kavya_kravchenko

[Meta] the nausea rule is doing its job and people should stop complaining

Question Well Actually ×3 Slow Clap ×1

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking nausea against triglycerides for 15 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

1,807 up / 336 down84% upvoted65 commentsid fotm2s18 Nov 2025

65 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/graph_it_gary302 points·8 months ago

ask your actual doctor, not us

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u/mikkel_kimani188 points·8 months ago

I am going to push back on this slightly.

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u/kavya_kravchenkoOP-11 points·8 months ago

The injection-site soreness passes. I kept a log and the timeline was the only useful thing. 6 weeks and it was basically gone.

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u/kavya_kravchenkoOP1 point·8 months ago

resting heart rate moved up 11 bpm and settled back down when I stopped escalating

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u/rekha_mbeki186 points·8 months ago

This is correct. The early fullness is horrible for three weeks and then just ends.

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u/sena_teixeira150 points·8 months ago

Did the reflux start before or after the dose increase?

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u/quiet_moderatormod76 points·8 months ago

nausea on day 2 is normal, nausea after week 13 is worth checking

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u/tomas_broberg60 points·8 months ago

hair loss is real and usually reversible when you stabilize

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u/hassan_castellanos52 points·8 months ago

the the food-noise thing passes. i promise. not medical advice.

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[deleted]72 points·8 months ago

[deleted]

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u/zeynep_zielinski106 points·8 months ago

Yeah, the constipation hit on day 17 for me too, not day 1.

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u/placebo_arm_pam88 points·8 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/reta_and_regret55 points·8 months ago

resting heart rate moved up 15 bpm and settled back down when I stopped escalating

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u/elin_lundgren22 points·8 months ago

Yeah, the constipation hit on day 10 for me too, not day 1.

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u/signe_villalobos102 points·8 months ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/kavya_kravchenkoOP63 points·8 months ago

The early fullness was genuinely awful for three weeks and then simply stopped. Week 79 me did not think I would make it to week 30.

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u/rohan_steiner0 points·8 months ago

This is correct. The muscle cramps is horrible for three weeks and then just ends.

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u/ayesha_radich17 points·8 months ago

The early fullness was genuinely awful for three weeks and then simply stopped.

Yes, exactly this, and it is the bit that took me 73 weeks to accept.

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u/karma_irrelevant11 points·8 months ago

Slight fix: the number was 99.0, not 98.9. Decimal point, but a fairly consequential one.

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u/laila_delgado41 points·8 months ago

the food-noise thing stops around week 71 for most people

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u/rina_bergstrom19 points·8 months ago

the food-noise thing stops around week 25 for most people

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u/sofia_wikstrom14 points·8 months ago

nausea on day 2 is normal, nausea after week 80 is worth checking

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u/ayesha_erdogan32 points·8 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/clara_weiss17 points·8 months ago

the early fullness passes. i promise. not medical advice.

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u/line_petrov46 points·8 months ago

Did the constipation start before or after the dose increase?

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