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c/survodutide·submitted 5 months ago by u/employer_carveout

three years of hepatic fat threads, summarised so you do not have to read them

Trial Databranch of 5 comments

Been lurking in c/t2dglp1 for about 4 months and finally have something worth posting. Short version: week 44, 2.4mg, and hepatic fat is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 9 threads, and the answers split roughly down the middle. What I actually want to know is…

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5 comments, started 5 months ago
u/samir_falk11 points·5 months ago

the safety profile is not just tirzepatide amplified

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u/isabela_nilsen6 points·5 months ago

Yeah, glucagon co-agonism is genuinely different.

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u/zeynep_villalobos-6 points·5 months ago

glucagon co-agonism has a different safety story

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u/rafael_sjoberg1 point·5 months ago

rodent dual agonist is investigation only

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u/renzo_yildiz1 point·5 months ago·edited

glucagon co-agonism has a different safety story

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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