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c/survodutide·posted 2 years ago by u/lina_ndiaye

[Question] the UK — has anyone got a straight answer on hepatic fat

Question

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking survodutide against triglycerides for 21 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

0 up / 0 down49% upvoted7 commentsid qh793k19 Feb 2024

7 comments

7 in this archive, depth 3

best — the order this archive was captured in

u/sena_teixeira4 points·2 years ago

This is correct. Do not generalise from tirzepatide.

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u/lina_ndiayeOP3 points·2 years ago

That is net peptide content, not purity. Different number, different meaning.

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u/isabela_nilsen1 point·2 years ago

the heart rate signal is real in the data

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u/incretin_ivyMOD4 points·2 years ago

Tracking number removed. It identifies both ends of a shipment.

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u/hub_opssite staff1 point·2 years ago

MASH claims need the trial and the biopsy endpoint

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u/lina_ndiayeOP0 points·2 years ago

hepatic fat and dual agonist are the story

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u/injection_site_iris1 point·2 years ago

rodent survodutide is investigation only

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About c/survodutide

Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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