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c/survodutide·submitted 9 months ago by u/whois_wanda

Denmark: dual agonist, and what it actually costs here

Trial Databranch of 8 comments

Been lurking in c/t2dglp1 for about 9 months and finally have something worth posting. Short version: week 26, 0.25mg, and hepatic fat is the bit I still cannot get a straight answer on. I have read the wiki, I have read the last 29 threads, and the answers split roughly down the middle. What I actually want to know…

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This branch

8 comments, started 9 months ago
u/trialwatch_theoMOD152 points·9 months ago

Tracking number removed. It identifies both ends of a shipment.

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u/vikram_mbeki71 points·9 months ago·edited

the safety profile is not just tirzepatide amplified

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u/zeynep_ndiaye99 points·9 months ago

the safety profile is not just tirzepatide amplified

Adding to this: dual agonist is doing more work than the comment implies.

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u/whois_wandaOP-24 points·9 months ago

the MASH indication changes the risk calculus

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u/vitamin_d_void1 point·9 months ago

do not generalise from tirzepatide

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u/dexa_twice_yearlybody comp1 point·9 months ago

Yeah, glucagon co-agonism is genuinely different.

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u/diego_szabo56 points·9 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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[deleted]23 points·9 months ago

[deleted]

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Survodutide-specific discussion: glucagon-receptor co-agonism, the hepatic fat and MASH resolution data, and how the side-effect profile compares with GIP-based dual agonism. Small community, high signal.

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