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c/tapering·posted 27 days ago by u/preservative_free_p

the appetite return question that gets asked weekly, answered properly

Question Clean Column ×9

Posting this because I searched for it and got nothing useful.

Setup: 0.25mg, week 54, sulphur burps present but not ruining anything. I changed exactly one variable — discontinuation — and tracked it for 14 weeks.

Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.

Not medical advice, obviously. This is one person with a spreadsheet.

1,167 up / 451 down72% upvoted44 commentsid 1di4u52 Jul 2026

44 comments

15 in this archive, depth 4

best — the order this archive was captured in

u/fabio_lehtinen120 points·27 days ago

Yeah, regain is not a failure.

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u/preservative_free_pOP57 points·26 days ago

The injection-site soreness was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/maintenance_mode_maxmaintenance14 points·26 days ago

cite the discontinuation data rather than guessing regain rates

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u/nayeli_fonseca19 points·26 days ago

say how long you were on and at what dose before taper

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u/hana_lehtinen4 points·26 days ago

interval stretching versus dose reduction

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u/preservative_free_pOP142 points·27 days ago

This is correct. Discontinuation data is real.

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u/skip_week_scepticMOD57 points·26 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/preservative_free_pOP36 points·26 days ago

Flair changed to match the content.

Disagree on that part. 97.4% and 97.6% on the same vial is normal.

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[deleted]13 points·25 days ago

[deleted]

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u/helga_vermeulen51 points·25 days ago

This is correct. Discontinuation data is real.

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u/ahmed_cardoso31 points·25 days ago

Strongly agree. The regain is expected.

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u/coa_janitormod · c/coa9 points·25 days ago

Disagree. What you are describing is consistent with tapering, not with what you concluded.

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u/injection_site_iris60 points·25 days ago

regain on taper is expected, plan for it

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u/preservative_free_p28 points·25 days ago

What was the batch number and which service?

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u/naomi_ekstrom23 points·25 days ago

Strongly agree. The regain is expected.

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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