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c/tirzepatide·submitted 2 years ago by u/copay_card_cc

[PSA] Mounjaro is not what most of this community thinks it is

Resultsbranch of 7 comments

Week 70 update. 46kg down from the start, early fullness basically gone since about week 15. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness. The part that surprised me is how much of this is…

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7 comments, started 2 years ago
u/halima_boateng288 points·2 years ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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u/tidy_vialdrawer_pls414 points·2 years ago

the 15mg is the top of the pen, not the required dose

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[removed]117 points·2 years ago

[removed by moderator]

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u/kaia_wojcik95 points·2 years ago

Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.

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u/laila_wikstrom47 points·2 years ago

SURMOUNT data is messier than STEP data but the weight loss is there

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u/tarek_kirchner13 points·2 years ago

Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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