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c/tirzepatide·submitted 2 years ago by u/taper_off_tabitha

three years of Mounjaro threads, summarised so you do not have to read them

Discussionbranch of 7 comments

Confession thread, sort of. I went from 5mg to 1.7mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 10 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway. So now I have…

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7 comments, started 2 years ago
u/rania_marchand204 points·2 years ago

do not crack the pen, we have been over this

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u/emil_barros52 points·2 years ago

I am going to push back on this slightly.

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u/zeynep_ndiaye25 points·2 years ago

do not crack the pen, we have been over this

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u/certified_referenceQC18 points·2 years ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/matias_salgado20 points·2 years ago·edited

the appetite change on tirz is more than just reduced hunger, it is different machinery

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u/dario_stanescu14 points·2 years ago

SURMOUNT data is messier than STEP data but the weight loss is there

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[deleted]75 points·2 years ago

[deleted]

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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