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c/tirzepatide·submitted 2 years ago by u/marta_dziedzic

[Vendor] QST order #6 — Denmark, 3 days, no drama, receipts inside

Side Effectsbranch of 10 comments

Something I noticed reading old threads that I have not seen said out loud. The advice on Mounjaro in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with…

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10 comments, started 2 years ago
u/swirl_dont_shakereconstitution1.4k points·2 years ago

The dual agonism story is real. The appetite is physically different from semaglutide alone.

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u/ingrid_correia1.1k points·2 years ago

the appetite change on tirz is more than just reduced hunger, it is different machinery

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u/halima_boateng333 points·2 years ago·edited

Slight fix: the number was 97.6, not 97.4. Decimal point, but a fairly consequential one.

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u/certified_referenceQC90 points·2 years ago

the 15mg is the top of the pen, not the required dose

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u/matias_salgado264 points·2 years ago

dual agonism is SURPASS, do not generalise from semaglutide

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u/two_mil_or_one80 points·2 years ago

the appetite change on tirz is more than just reduced hunger, it is different machinery

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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