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c/tirzepatide·submitted 2 years ago by u/neha_falk

[Discussion] we are measuring Zepbound at the wrong time and calling it noise

Discussionbranch of 7 comments

Posting this because I searched for it and got nothing useful. Setup: 2.5mg, week 84, sulphur burps present but not ruining anything. I changed exactly one variable — Mounjaro — and tracked it for 9 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I…

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7 comments, started 2 years ago
u/coring_the_stopper71 points·2 years ago·edited

SURMOUNT data is messier than STEP data but the weight loss is there

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u/cormac_pereira18 points·2 years ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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u/discount_math_dm14 points·2 years ago

Is that on Mounjaro pens or research tirzepatide?

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u/hair_shed_hannah7 points·2 years ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

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u/aurel_lindqvist32 points·2 years ago

Did the muscle cramps feel the same as on tirz or genuinely different?

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u/certified_referenceQC20 points·2 years ago

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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