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c/tirzepatide·submitted 2 years ago by u/zeynep_ndiaye

am I the only one who found Mounjaro harder than the injections

Resultsbranch of 10 comments

Posting this because I searched for it and got nothing useful. Setup: 2.5mg, week 23, sulphur burps present but not ruining anything. I changed exactly one variable — Mounjaro — and tracked it for 2 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I…

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10 comments, started 2 years ago
u/titration_marshalMOD805 points·2 years ago

Retitled to remove editorialising. Put the evidence in the body.

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u/georgi_chowdhury674 points·2 years ago

stalled on sema, tried tirz, and the curves were actually different shapes

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u/bastian_ekstrom982 points·2 years ago

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

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u/noor_hovland378 points·2 years ago

dual agonism is dual agonist, do not generalise from semaglutide

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u/zeynep_ndiayeOP0 points·2 years ago

SURMOUNT data is messier than STEP data but the weight loss is there

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u/gustav_vermeulen446 points·2 years ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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u/zeynep_ndiaye110 points·2 years ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

Disagree on that part. 98.4% and 98.3% on the same vial is normal.

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u/fatima_wojcik-31 points·2 years ago

Small correction: the trial was 2 weeks, not 29. Does not change your point but people will quote it.

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u/ewan_marchand75 points·2 years ago

do not crack the pen, we have been over this

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u/endpoint_creep62 points·2 years ago

Did the fatigue feel the same as on tirz or genuinely different?

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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