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c/tirzepatide·submitted 9 months ago by u/line_petrov

does Zepbound actually matter or is it forum lore at this point

Titrationbranch of 8 comments

Genuinely asking, not being difficult. Everyone in c/semaglutide repeats that dual agonist is important. I believe it, but I have never seen anyone show why, and when I search I get 4 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

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8 comments, started 9 months ago
u/halima_boateng200 points·9 months ago·edited

SURMOUNT data is messier than STEP data but the weight loss is there

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u/kaia_cabrera65 points·9 months ago·edited

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

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u/line_petrovOP74 points·9 months ago

the 15mg is the top of the pen, not the required dose

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u/kaia_wojcik88 points·9 months ago

the appetite change on tirz is more than just reduced hunger, it is different machinery

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u/taper_off_tabitha31 points·9 months ago

the appetite change on tirz is more than just reduced hunger, it is different machinery

Disagree on that part. 98.1% and 98.9% on the same vial is normal.

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u/aksel_kjaer109 points·9 months ago

Respectfully this is a sample of one presented as a finding.

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u/britt_okwuosa76 points·9 months ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

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u/sten_bhattacharya34 points·9 months ago

Is that on Mounjaro pens or research tirzepatide?

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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