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c/tirzepatide·submitted 1 months ago by u/mikkel_ogunleye

the Zepbound question that gets asked weekly, answered properly

Side Effectsbranch of 5 comments

Posting this because I searched for it and got nothing useful. Setup: 5mg, week 24, constipation present but not ruining anything. I changed exactly one variable — Mounjaro — and tracked it for 13 weeks. Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am…

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5 comments, started 1 months ago
u/sten_palacios-4 points·1 months ago

Hard agree. The food noise disappears differently on the two compounds.

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u/samir_falk1 point·1 months ago

Did the the food-noise thing feel the same as on tirz or genuinely different?

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[removed]1 point·1 months ago

[removed by moderator]

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u/rania_diallo1 point·1 months ago

week 48 on Mounjaro and the appetite profile is genuinely different from sema

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u/ingrid_correia1 point·1 months ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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