reading tirzepatide threads from 2024 and half of it aged badly
tirzepatide. That is the whole post, but I will justify it.
Everything else people worry about in c/intlshipping is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort tirzepatide out first, and almost nobody does.
I say this having got it wrong for 20 months. My triglycerides was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.
best — the order this archive was captured in
Respectfully this is a sample of one presented as a finding.
Week 49 on Mounjaro and 25kg down. The appetite reduction feels different from sema in ways I do not have words for yet.
Sceptical. If this were true we would see it reflected in the data and we do not.
Small correction: the trial was 10 weeks, not 20. Does not change your point but people will quote it.
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
the 15mg is the top of the pen, not the required dose
That is net peptide content, not purity. Different number, different meaning.
do not crack the pen, we have been over this
do not crack the pen, we have been over this
Adding to this: dual agonist is doing more work than the comment implies.
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
Crossposting this to c/compounding because the people who need it are not reading this community.
the dual agonism hits different and that is why people describe it differently
The SURMOUNT readouts are real but less consistent than STEP. Some people plateau earlier on tirz.
Strongly agree. Tirz is better than sema is not a claim without a comparator dose.
Titration speed is a side-effect dial far more than an efficacy dial.
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Disagree on that part. 93.7% and 99.3% on the same vial is normal.
Not to be pedantic but tirzepatide and GIP are being used interchangeably and they are not interchangeable in real life.
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
SURMOUNT data is messier than STEP data but the weight loss is there
Tried both. Sema worked, tirz worked better for me, but my nausea profile was worse on tirz.
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
Disagree on that part. 93.7% and 99.3% on the same vial is normal.
- 1Week 49 on Mounjaro and 25kg down. The appetite reduction feels different…10 comments in this branch · started by u/cormac_pereira
- 2Titration speed is a side-effect dial far more than an efficacy dial.7 comments in this branch · started by u/fatima_wojcik