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c/tirzepatide·submitted 1 year ago by u/certified_reference

reading tirzepatide threads from 2024 and half of it aged badly

Discussionbranch of 7 comments

tirzepatide. That is the whole post, but I will justify it. Everything else people worry about in c/intlshipping is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort tirzepatide out first, and almost nobody does. I say this having got it wrong for 20…

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7 comments, started 1 year ago
u/fatima_wojcik22 points·1 year ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/sten_palacios11 points·1 year ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

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u/certified_referenceQC7 points·1 year ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

Disagree on that part. 93.7% and 99.3% on the same vial is normal.

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u/mod_cold_roommod · c/coldchain3 points·1 year ago

Not to be pedantic but tirzepatide and GIP are being used interchangeably and they are not interchangeable in real life.

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u/hugo_bergstrom1 point·1 year ago

Did you stay on semaglutide or switch? The outcome is different if you are comparing.

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u/certified_referenceOPQC1 point·1 year ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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u/dexa_twice_yearlybody comp2 points·1 year ago

SURMOUNT data is messier than STEP data but the weight loss is there

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Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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