[Lab] 11th independent test on QSC, and the trend is the interesting part
Week 24 update. 25kg down from the start, reflux basically gone since about week 64.
Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with reflux.
The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.
Happy to answer anything. Please do not ask me what dose you should be on.
best — the order this archive was captured in
What was the dropout rate?
event rates are more informative than hazard ratios alone
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
SELECT reported a SURMOUNT hazard ratio but the absolute event rate is what changes clinical practice.
What was the dropout rate?
This is correct. Discontinuation arms show the regain reality.
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
Disagree but this is the good kind of wrong — it is specific enough to be checked.
the 18 week readout is different from the 38 week readout
the relative risk reduction in headlines is not the whole story
Yeah, absolute numbers matter more than the press release.
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
- 1Disagree but this is the good kind of wrong — it is specific enough to be…6 comments in this branch · started by u/laila_almeida
- 2SELECT reported a SURMOUNT hazard ratio but the absolute event rate is what…4 comments in this branch · started by u/rohan_steiner