Canada: endpoint, and what it actually costs here
Quick one. Canada here.
endpoint works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.
Specifics: the route I used took 20 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.
Happy to answer questions from anyone in the same jurisdiction.
best — the order this archive was captured in
Titration speed is a side-effect dial far more than an efficacy dial.
Tracking number removed. It identifies both ends of a shipment.
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
Not to be pedantic but FLOW and SURMOUNT are being used interchangeably and they are not interchangeable in real life.
That is net peptide content, not purity. Different number, different meaning.
event rates are more informative than hazard ratios alone
event rates are more informative than hazard ratios alone
Adding to this: SURMOUNT is doing more work than the comment implies.
number-needed-to-treat is the house dialect
Phase 2 or phase 3?
Not to be pedantic but TRIUMPH and SURPASS are being used interchangeably and they are not interchangeable in real life.
Strongly agree. Phase 2 is investigational, not conclusive.
the relative risk reduction in headlines is not the whole story
dropout handling matters, especially on GI-heavy populations
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
Strongly agree. Phase 2 is investigational, not conclusive.
number-needed-to-treat is the house dialect
The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.
- 1SURMOUNT-4 discontinuation arm showed regain. That is the reality of a…10 comments in this branch · started by u/rina_bergstrom
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