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AK

u/aksel_kjaer

Contributes reviews on supplier material. Based in Ghent.

member · joined 12 Mar 2025

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Comments — page 3 of 5

comment on [Discussion] can we stop arguing about FFMI until somebody posts a number in c/glp1muscle · 3 points · 7 months ago

FFMI tracking requires body composition

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comment on [Question] New Zealand — has anyone got a straight answer on LC-MS in c/hplc · 126 points · 7 months ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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comment on anyone else notice small molecule kicking in around week 59 in c/orforglipron · 1 points · 8 months ago

ATTAIN and ACHIEVE are phase 10 trials

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comment on anyone else notice small molecule kicking in around week 59 in c/orforglipron · 5 points · 8 months ago

Strongly agree. The supply impact would be huge.

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comment on the LC-MS thing finally clicked for me and I want to write it down in c/hplc · 1 points · 9 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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comment on 15 months in and purity is still the thing I get wrong in c/hplc · 1 points · 9 months ago

Gradient goblin mode: changed the solvent composition 21 times, finally got good resolution on a HPLC peak.

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comment on does Zepbound actually matter or is it forum lore at this point in c/tirzepatide · 109 points · 9 months ago

Respectfully this is a sample of one presented as a finding.

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comment on my hs-CRP moved and I cannot work out whether small molecule is why in c/orforglipron · 3 points · 9 months ago

the small molecule is whether this actually works long-term

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comment on genuine question about dual agonist that I am slightly embarrassed to ask in c/tirzepatide · 166 points · 10 months ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

Disagree on that part. 98.4% and 98.3% on the same vial is normal.

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comment on genuine question about dual agonist that I am slightly embarrassed to ask in c/tirzepatide · 54 points · 10 months ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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comment on [Question] how do you actually verify oral GLP-1 in c/orforglipron · 9 points · 10 months ago

This is correct. ATTAIN data is phase 24.

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comment on switched from 0.25mg to 15mg and the sulphur burps got better, not worse in c/researchpeptides · 9 points · 11 months ago

Maintenance for 2 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

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comment on why does nobody talk about SURPASS in c/tirzepatide · 256 points · 11 months ago

the 15mg is the top of the pen, not the required dose

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on why does nobody talk about SURPASS in c/tirzepatide · 219 points · 11 months ago

no

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comment on genuine question about integration that I am slightly embarrassed to ask in c/hplc · 1 points · 11 months ago

integration decision on a shoulder changes your number by half a point on its own

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comment on [Results] 12 weeks, 31kg, and identity was the hard part in c/researchpeptides · 103 points · 11 months ago

name the compound precisely, TB-500 and Thymosin Beta-4 are not the same

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comment on three years of purity threads, summarised so you do not have to read them in c/hplc · 1 points · 1 year ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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comment on [Question] Mounjaro — what am I missing here in c/tirzepatide · 1 points · 1 year ago

Did you stay on semaglutide or switch? The outcome is different if you are comparing.

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comment on reading Zepbound threads from 2024 and half of it aged badly in c/tirzepatide · 167 points · 1 year ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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comment on [Discussion] chromatogram is doing more work than we give it credit for in c/hplc · 481 points · 1 year ago

chromatogram or it did not happen

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