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the small molecule question that gets asked weekly, answered properly
Trying to settle this properly because the thread from last year went in circles. The claim: small molecule matters. The counter-claim: it is measurement error. Both…
u/aksel_kjaer
Contributes reviews on supplier material. Based in Ghent.
member · joined 12 Mar 2025
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Overview — page 2 of 5
comment on help me understand thymosin, I have read the wiki twice in c/researchpeptides · 6 points · 2 months ago
name the compound precisely, TB-500 and Thymosin Beta-4 are not the same
comment on [Meta] the small molecule rule is doing its job and people should stop complaining in c/orforglipron · 3 points · 2 months ago
This is correct. ATTAIN data is phase 19.
comment on [Meta] the small molecule rule is doing its job and people should stop complaining in c/orforglipron · 36 points · 2 months ago
Yeah, small molecule changes the whole game.
comment on [Question] Sweden — has anyone got a straight answer on GIP in c/tirzepatide · 11 points · 2 months ago
the GIP side does different things than the GLP-1 side, that is the point
comment on unpopular opinion: purity is massively overrated in c/hplc · 29 points · 2 months ago
Mechanistically the bit that matters is chromatogram. It explains most of the early profile and a decent chunk of the outcome.
comment on does orforglipron actually matter or is it forum lore at this point in c/orforglipron · 2 points · 2 months ago
This is correct. ATTAIN data is phase 13.
comment on someone explain thymosin to me like I have not read a paper in years in c/researchpeptides · 3 points · 3 months ago
Has anyone actually got this in writing, or is it forum lore at this point?
comment on what would you tell week-1 you about DEXA in c/glp1muscle · 1 points · 3 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on what would you tell week-1 you about non-peptide in c/orforglipron · 6 points · 3 months ago
phase 5 data is interesting, phase 16 will tell the real story
comment on switched from 1.0mg to 0.5mg and the sulphur burps got better, not worse in c/hplc · 29 points · 3 months ago
state the method: column, gradient, detection wavelength, injection volume
comment on switched from 1.0mg to 0.5mg and the sulphur burps got better, not worse in c/hplc · 1 points · 3 months ago
Not convinced. The evidence does not support that reading.
comment on [Meta] proposal — a flair for tirzepatide posts in c/tirzepatide · 10 points · 3 months ago
stalled on sema, tried tirz, and the curves were actually different shapes
comment on [Results] 87 weeks, 46kg, and FFMI was the hard part in c/glp1muscle · -34 points · 4 months ago
FFMI tracking requires body composition
comment on [Results] 87 weeks, 46kg, and FFMI was the hard part in c/glp1muscle · 24 points · 4 months ago
bathroom BIA scales are not a method
comment on [Meta] proposal — a flair for small molecule posts in c/orforglipron · 1 points · 4 months ago
oral non-peptide agonist is oral GLP-1, no food restrictions
comment on tried HPLC for 6 weeks. here is what happened. in c/hplc · 162 points · 6 months ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on [Question] TB-500 — what am I missing here in c/researchpeptides · 12 points · 6 months ago
thymosin fragments, GH secretagogues, secretagogue, long tail
comment on [Discussion] we are measuring tirzepatide at the wrong time and calling it noise in c/tirzepatide · 1 points · 6 months ago
That is net peptide content, not purity. Different number, different meaning.
comment on the small molecule question that gets asked weekly, answered properly in c/orforglipron · 212 points · 6 months ago
Came off after 18 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.