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u/annika_fonseca

Contributes reviews on supplier material. Based in Mysuru.

member · joined 15 Jun 2025

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Comments — page 2 of 5

comment on three years of mechanism threads, summarised so you do not have to read them in c/glp1science · 219 points · 3 months ago

incretin physiology is appetite, the mechanism layer

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comment on what would you tell week-1 you about SELECT in c/trialwatch · 8 points · 3 months ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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comment on [Results] 91 weeks on 1.0mg, full numbers, ask me anything boring in c/glp1muscle · 391 points · 3 months ago

Has anyone actually got this in writing, or is it forum lore at this point?

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comment on anyone else notice endpoint kicking in around week 19 in c/trialwatch · 43 points · 4 months ago

STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix

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comment on genuine question about sarcopenia that I am slightly embarrassed to ask in c/glp1muscle · -9 points · 4 months ago

This is correct. DEXA is the standard.

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comment on am I the only one who found half-life harder than the injections in c/glp1science · 26 points · 5 months ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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comment on [PSA] EMS is not what most of this community thinks it is in c/intlshipping · 169 points · 5 months ago

customs clearance often adds 2 days, factor that in

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comment on small win: SURMOUNT stopped being a problem at week 65 in c/trialwatch · 33 points · 5 months ago

I am going to push back on this slightly.

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comment on someone explain shipping to me like I have not read a paper in years in c/intlshipping · 59 points · 5 months ago

packaging quality matters on the 15-hour segments

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comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 14 points · 5 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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comment on unpopular opinion: USDC is massively overrated in c/cryptopay · 5 points · 5 months ago

Crossposting this to c/bloodwork because the people who need it are not reading this community.

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comment on the hazard ratio thing finally clicked for me and I want to write it down in c/trialwatch · 43 points · 6 months ago

Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.

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comment on pharmacology — 17 things I got wrong before I got it right in c/glp1science · 20 points · 7 months ago

incretin physiology is half-life, the mechanism layer

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comment on unpopular opinion: DHL is massively overrated in c/intlshipping · 39 points · 7 months ago

Strongly agree. Customs adds unpredictable delay.

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comment on three years of protein threads, summarised so you do not have to read them in c/glp1muscle · 109 points · 8 months ago

lean mass retention is the 54 week conversation

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comment on Denmark: dual agonist, and what it actually costs here in c/survodutide · 22 points · 9 months ago

glucagon co-agonism has a different safety story

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comment on the appetite thing finally clicked for me and I want to write it down in c/glp1science · 40 points · 9 months ago

the 19-day half-life means week 19 is still ramp-up pharmacokinetically

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comment on [Meta] the FFMI rule is doing its job and people should stop complaining in c/glp1muscle · 30 points · 10 months ago

resistance training is lean mass not optional

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comment on [PSA] chargeback is not what most of this community thinks it is in c/cryptopay · 19 points · 11 months ago

Strongly agree. Escrow is non-negotiable for groups.

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comment on [Meta] proposal — a flair for chargeback posts in c/cryptopay · 13 points · 12 months ago

the 7% discount versus 9% network fees

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