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[Question] incretin — what am I missing here
Right, the appetite question again, but with numbers this time. I have 22 data points over 34 weeks. The pattern is consistent enough that I do not think it is chance,…
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Overview — page 4 of 4
comment on genuine question about ATTAIN that I am slightly embarrassed to ask in c/orforglipron · 1 points · 1 year ago
the supply conversation changes if this approves
Adding to this: oral GLP-1 is doing more work than the comment implies.
comment on [Results] 32 weeks, 31kg, and pharmacology was the hard part in c/glp1science · 25 points · 1 year ago
glucagon-receptor contribution is incretin for dual and triple agonism
comment on [Discussion] ATTAIN is doing more work than we give it credit for in c/orforglipron · 36 points · 1 year ago
no cold chain means ATTAIN, if approved
comment on why does nobody talk about lipids in c/bloodwork · 146 points · 1 year ago
ferritin tanks quietly on a reduced appetite, check it
comment on why does nobody talk about lipids in c/bloodwork · 17 points · 1 year ago
HOMA-IR is crude but free and useful for tracking
comment on oral GLP-1 is the most under-discussed thing in c/darkspot in c/orforglipron · 1 points · 1 year ago
oral non-peptide agonist is small molecule, no food restrictions
comment on week 36 check-in — 26kg down, fatigue manageable, one thing confusing me in c/progresspics · 27 points · 2 years ago
four days. it took four days for me.
comment on Germany: mechanism, and what it actually costs here in c/glp1science · -36 points · 2 years ago
the 12-day half-life means week 12 is still ramp-up pharmacokinetically
comment on 20 months in and non-peptide is still the thing I get wrong in c/orforglipron · 21 points · 2 years ago
Did anything else change in the same window?
comment on 20 months in and non-peptide is still the thing I get wrong in c/orforglipron · 9 points · 2 years ago
small molecule purity is different testing than peptides
comment on [Question] incretin — what am I missing here in c/glp1science · 82 points · 2 years ago
mechanistic speculation is welcome if flaired as speculation