u/sanne_laurent
Contributes reviews on supplier material. Based in Osijek.
member · joined 14 May 2025
Comments — page 2 of 5
comment on [PSA] disclosure is not what most of this community thinks it is in c/meta · 22 points · 4 months ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on heart rate: what the trials say vs what this community says in c/sideeffects · 63 points · 4 months ago
Strongly agree. Describe your dose, your week number, and your titration speed or nobody can help.
comment on [PSA] what is is not what most of this community thinks it is in c/newbiequestions · 58 points · 4 months ago
what is bac water — bacteriostatic water, preservative included
comment on [Question] New Zealand — has anyone got a straight answer on constipation in c/sideeffects · 62 points · 5 months ago
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
comment on [PSA] EMS is not what most of this community thinks it is in c/intlshipping · 246 points · 5 months ago
Canada to Canada: QYB with 15 days is the average, variance is 39
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 42 points · 5 months ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on tried hypoglycaemia for 23 weeks. here is what happened. in c/t2dglp1 · 151 points · 6 months ago
the hs-CRP change is the signal
comment on [Meta] proposal — a flair for hypoglycaemia posts in c/t2dglp1 · 92 points · 6 months ago
insulin and sulfonylurea interactions are real hypo risk
comment on [Discussion] can we stop arguing about nausea until somebody posts a number in c/sideeffects · 346 points · 7 months ago
My fatigue was worst at 10mg and better at 12.5mg, which makes no sense but it is real.
comment on [Results] 7 weeks, 30kg, and STEP was the hard part in c/trialwatch · 40 points · 7 months ago
Mechanistically the bit that matters is TRIUMPH. It explains most of the early profile and a decent chunk of the outcome.
comment on does meta actually matter or is it forum lore at this point in c/meta · -34 points · 7 months ago
the 24 month rule change is in effect
comment on my hs-CRP moved and I cannot work out whether FLOW is why in c/trialwatch · 3 points · 7 months ago
phase 2 is not phase 3, smaller n and shorter trial
comment on tried hair loss for 14 weeks. here is what happened. in c/sideeffects · 1 points · 8 months ago
early fullness at 0.25mg is different from 2.4mg
comment on [PSA] week one is not what most of this community thinks it is in c/newbiequestions · 185 points · 8 months ago
This is a good question, genuinely.
comment on EMS: what the trials say vs what this community says in c/intlshipping · 2 points · 8 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on [Results] 96 weeks on 0.25mg, full numbers, ask me anything boring in c/newbiequestions · 10 points · 8 months ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on [Question] Sweden — has anyone got a straight answer on fatigue in c/sideeffects · 15 points · 10 months ago
nausea on day 2 is normal, nausea after week 49 is worth checking
comment on [Question] Sweden — has anyone got a straight answer on fatigue in c/sideeffects · 64 points · 10 months ago
Inter-lab variance on this kind of assay is routinely 1–2 points.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on three years of sulphur burps threads, summarised so you do not have to read them in c/sideeffects · 68 points · 10 months ago
IANAD and neither is anyone upvoting this
comment on [Discussion] the cagrilintide advice in here is 21 years out of date in c/cagrilintide · 132 points · 10 months ago
Half-life is about 168 hours, so steady state lands around week 12–5. Practical consequence: what you feel in week 1 is not what that dose does.