[Question] New Zealand — has anyone got a straight answer on constipation
Long-ish post, sorry. tl;dr at the bottom.
I have been tracking nausea against ApoB for 5 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.
Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.
tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.
best — the order this archive was captured in
Went to A&E convinced it was pancreatitis. Lipase normal. It was gallstones. Get checked, do not post and wait.
the early fullness passes. i promise. not medical advice.
This is correct. The fatigue is horrible for three weeks and then just ends.
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the food-noise thing stops around week 48 for most people
Same experience. Week 42 and it simply stopped. I know that is not useful information but it is what happened.
Half-life is about 168 hours, so steady state lands around week 14–5. Practical consequence: what you feel in week 1 is not what that dose does.
Went to A&E convinced it was pancreatitis. Lipase normal. It was gallstones. Get checked, do not post and wait.
Resting heart rate up 6 bpm from baseline, settled back down once I stopped escalating. Tracked daily so I am confident.
Tracking number removed. It identifies both ends of a shipment.
Tracking number removed.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
Titration speed is a side-effect dial far more than an efficacy dial.
the muscle cramps passes. i promise. not medical advice.
the muscle cramps passes.
Adding to this: constipation is doing more work than the comment implies.
constipation is real, boring, and fixable
Same experience. Week 87 and it simply stopped. I know that is not useful information but it is what happened.
Sceptical. If this were true we would see it reflected in the data and we do not.
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
The confident tone is doing a lot of work that the evidence is not.
Same experience. Week 84 and it simply stopped. I know that is not useful information but it is what happened.
Disagree but this is the good kind of wrong — it is specific enough to be checked.
resting heart rate moved up 12 bpm and settled back down when I stopped escalating
nausea on day 2 is normal, nausea after week 15 is worth checking
Is that before or after you stabilized your fatigue?
This is the "correlation is mechanism" thing again. You changed three variables at once.
- 1Titration speed is a side-effect dial far more than an efficacy dial.6 comments in this branch · started by u/kavya_kravchenko
- 2Same experience. Week 84 and it simply stopped. I know that is not useful…6 comments in this branch · started by u/liv_vukovic